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Can Male Pheromones Attract Other Men? The Science of Same-Sex Chemosignals

Can male pheromones attract other men? Karolinska brain-imaging shows gay men's hypothalami respond to male signals. Here is the science, dosing, and what works.

By William M. Updated
Two men close together at a bar, low light, pheromone attraction theme

Yes, male pheromones can attract other men, with limits. Brain scans show gay men’s hypothalami respond to the male compound androstadienone the way straight women’s do, while straight men’s brains treat it as ordinary smell. Pheromones amplify attraction that is already there. They do not change orientation, and they never guarantee results.

Two things are coming further down. A customer once asked me about a guy at his gym, and I gave him an answer he did not want to hear. And one molecule from these brain studies is missing from the formulas I carry, on purpose, for a reason that surprises people.

What the Karolinska brain scans found

The best-known work comes from Ivanka Savic’s team at Sweden’s Karolinska Institute, published in PNAS in 2005. They used PET scans, which track blood flow in the brain, on straight men, straight women and gay men. Each person smelled androstadienone (AND), a compound found in male sweat, and estratetraenol (EST), found in female urine.

In straight women, the male compound switched on the hypothalamus, the small region that steers sex drive and hormones. Gay men showed the same hypothalamic activation. Straight men’s brains handled the compound through ordinary smell areas, such as the piriform cortex, and the hypothalamus stayed quiet.

I like to be precise about what this shows. Thirty-six people took part, split into three groups, and the scans measured brain activation, not attraction or behavior. Savic herself noted that the study does not settle cause and effect, and that the activation pattern does not suggest conscious thinking. The response runs below awareness, which means your brain answers before you decide anything.

When I first read this paper, my instinct was to check it against real rooms, the way I check every study. I had spent plenty of nights out by then noticing who held eye contact and who looked past me, and the idea of a response running below awareness matched what I had felt more than once. I could never explain why a conversation clicked with one guy and stalled with another, and this gave me a better way to think about it.

Later PET work points the same way, grouping gay men with women on the same hypothalamic pathway for AND. The molecule has its own story, and I cover the androstadienone effects separately.

How scent changes what a man sees

Brain activation is one thing. Does it change what a man actually perceives? A Current Biology study says it does. Researchers showed people point-light walkers, a handful of moving dots that read as a human figure, morphed step by step from male to female.

Straight women who smelled androstadienone leaned toward seeing the walker as more masculine, and straight men did not. Gay men responded much like the straight women. The shift was about 8% when the visual cues were ambiguous.

Nobody had to notice a smell for this to work. Wen Zhou of the Chinese Academy of Sciences put it plainly: the nose can read gender from body secretions even when you think you smell nothing. I think of that every time a customer emails to say a night felt different and he cannot say why.

Body odor tests from the Monell Center

Those first two studies used one compound at a time. Martins, Wysocki and colleagues at the Monell Chemical Senses Center tested whole body odor instead. They asked 82 straight and gay men and women to rate underarm sweat from 24 donors.

The donors prepared carefully. For nine days they used unscented soap and shampoo and ate plain food, then wore cotton pads under their arms for one day. I did something similar when I ran my own protocol, washing my underarms with water only and skipping scented products. I remember being surprised at how much cleaner and more neutral my own skin smelled once I stopped covering it up.

Gay men preferred the odors of gay men and straight women. Straight men, straight women and lesbian women liked gay men’s odors least. Wysocki summed up what the team took from it:

“Our findings support the contention that gender preference has a biological component that is reflected in both the production of different body odors and in the perception of and response to body odors.” (Charles Wysocki, PhD, Monell Chemical Senses Center)

The research on male same sex pheromones keeps landing in the same place: skin chemistry carries signals before anyone says hello. Pure pheromone molecules are close to odorless. The smell people notice is skin bacteria working on them over hours, which is why all of this happens below the level of “I smell something.”

What male pheromones can and cannot do to men

Pheromones amplify. They do not force. A straight man’s brain treats male scent as ordinary smell, so no blend will turn a straight guy toward you, and any brand that tells you otherwise is selling a late-night infomercial.

A customer emailed me a while back asking whether a pheromone would get a guy at his gym to notice him. I told him straight: it will not change who the other man is attracted to. If the guy is open to men, a good blend might warm those first few moments. If he is not, nothing in a bottle fixes that. He wrote back that he preferred the honest answer, and I trust that reply more than any thank-you for hype.

So what is the real male pheromones effect on males? A warmer start with men who are already open to you. Eye contact lingers a little longer, and he may stay a little closer. Scent opens the door, and you still have to walk through it and say something.

Keep your cologne light while you do. A loud cologne masks the signal rather than pushing anyone away. That is why I wear an unscented base like Nude under whatever fragrance I already own.

Which molecules suit men seeking men

Pheromones do not all do the same job. Mix the wrong ones and your blend sends a signal you never intended.

Androstenone

Androstenone occurs in male sweat and reads as status and sexual tension. In a gay bar or on a crowded dance floor, it adds a harder, more physical presence.

Androsterone

Androsterone brings steady authority and trust, and it softens a strong blend. That is why I like androstenone over an androsterone base: you keep the presence and become easier to approach. If you want to see how androstenone differs from its cousin, I wrote up androstenone versus androstenol.

Androstadienone (A1)

Here is the payoff on the missing molecule. A1 is the compound from the scans, and it raises cortisol in the women who smell it, alongside better mood and focus. Calm, relaxed and bonding all fit.

Liquid Alchemy Labs leaves A1 out of its blends on purpose, because ease is not passion. At a party it can steer a night toward a pleasant chat instead of real tension.

The practical logic is a ratio: androstenone forward, androsterone balancing it.

Picking a blend for the night

People search for the best pheromones perfume to attract a man, but the room picks the winner more than the bottle does. I have stood in both kinds of rooms: loud clubs where I wanted presence, and quiet bar corners where that same presence felt like too much.

In a crowded club, go androstenone-led. An androstenone cologne gives you a firmer presence among a lot of guys trying to catch someone’s eye. A quiet date over drinks wants something warmer and lighter, since heavy dominance feels strange when you sit close together.

If you want a starting point, pheromones for gay men built around androstenone over an androsterone base are what I wear. Nude is unscented, so it slips under your own cologne. Possess Alpha is the scented option for an evening out.

Whichever you pick, cologne and pheromones go on separate spots, never the same one.

Where and how to wear them

My early bar nights taught me this the hard way. I once put on far more of a strong formula than I needed, sure that more would work harder. The whole night felt like I was shouting across the room. When I cut back, I felt calmer and the conversations came easier. Restraint read as confidence, not as less.

Clean skin comes first, since the smell people notice is skin bacteria working on near-odorless molecules over hours. Then pick your spot:

  • Neck: the best spot, close to where someone leans in to talk.
  • Wrists: okay, though they move around a lot.
  • Clean armpits: a fine option if the skin is freshly washed.

Start with one or two small drops, and see my guide on how to apply pheromone cologne for more on placement. Stacking more rarely helps.

Store the bottle away from heat and direct sunlight.

Male pheromones will not turn a head on their own. Worn lightly on clean skin, though, they give the right man a warmer first impression, and the rest is up to you. If you want the scented route for a night out, Possess Alpha is the one I would point you to.

Frequently Asked Questions

Frequently asked

Can male pheromones attract other men?

Yes, with limits. Brain scans from the Karolinska Institute show gay men's hypothalami respond to androstadienone the way straight women's do. Straight men's brains treat it as ordinary smell, and pheromones amplify attraction that is already there rather than create it.

Which pheromone molecules are most effective for gay men?

Androstenone leading with androsterone for balance is the pairing I trust. Androstenone carries status and sexual tension, while androsterone adds steady authority and trust so the blend does not read as pushy. I leave androstadienone out because ease is not passion.

Will male pheromones make straight men attracted to me?

No. Pheromones amplify attraction that already exists, and they do not change orientation. In the Karolinska scans, straight men's brains handled the male compound as ordinary smell, with no hypothalamic response.

Can other people consciously smell that I am wearing pheromones?

Mostly no. Pure pheromone molecules are close to odorless, and the smell people notice is your skin bacteria working on them over hours. Keep your cologne light and on a separate spot, because a loud one masks the signal.

Why should I avoid androstadienone for nightlife and hookups?

Because it brings ease, not heat. Androstadienone raises cortisol in the women who smell it, alongside better mood and focus, so calm, relaxed and bonding all fit. That suits a quiet conversation, but ease is not passion, so I leave it out for nights out.

How many drops of pheromone oil should I use?

Start with one or two small drops on clean skin at the neck. Restraint beats stacking, and you can always add a touch later. Keep your cologne on a separate spot so the two do not fight.

Do pheromones work on dating apps?

No. Pheromones travel through the air from your skin, so they help once you are in the same room, not through a phone screen. Use the app to get the date and the blend to support the first moments across the table.

How long does a pheromone application last on skin?

It varies with your skin and body heat. Oil-based formulas tend to diffuse slowly, while alcohol-based sprays project further at first and need a refresh sooner. Reapply lightly instead of stacking, and keep the bottle away from heat and direct sunlight.